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Showing posts with label Study. Show all posts
Showing posts with label Study. Show all posts

Tuesday, June 14, 2011

Study Reveals Bariatric Surgery Less Effective in Middle-Aged Adults (ContributorNetwork)

If you're morbidly obese and middle-aged, weight-loss surgery may not decrease your chances of dying, according to a study published Sunday in the online Journal of the American Medical Association. Morbidly obese is defined as having a body mass index greater than 39 and generally means someone who is 100 pounds or more overweight.

Researchers were interested in studying the mortality rates of middle-aged and older adults after bariatric surgery. Data available prior to this study was based almost solely on young, white females who had had the weight-loss surgery. That group of individuals has a lower incidence of mortality related to obesity even before bariatric surgery than do older adults, according to study researchers.

The purpose of the study was to determine the effectiveness of weight-loss surgery in populations with an increased risk of death related to obesity; these populations were identified as being highest in men and minority populations.

The research team studied follow-up data for 850 men with a mean age of 49.5 years and a mean BMI of 47.4 for an average of 6.2 years. The men in the study had the weight-loss surgery between the years 2000 and 2006. Their mortality (death) rate was compared to a control group of 41,000 other men who did not have the surgery, reports Yahoo! News. All the men were patients at medical centers of Veterans Affairs.

Researchers concluded that bariatric surgery in morbidly obese middle-aged men did not decrease their risk of death compared with care that did not include the surgery. Still, this population may opt for weight-loss surgery based on factors other than mortality rate, such as the reduction of body weight, control of obesity-related health conditions and improved quality of life.

In the United States, weight-loss surgery usually involves one of four procedures, explains the Weight-Control Information Network. The four procedures, each with its own risks and benefits, are: adjustable gastric band (AGB); Roux-en-Y gastric bypass (RYGB); biliopancreatic diversion with a duodenal switch (BPD-DS); and vertical sleeve gastrectomy (VSG). The AGB works by decreasing food intake while the other surgeries involve not only the decreased ability to take in food but also affect food absorption and other factors.

Your physician will weigh conditions such as your health, obesity-related health conditions and your eating behaviors in helping to determine which, if any, of the weight-loss surgeries would be to your benefit. The outcome of this new study into mortality rates following bariatric surgery may be a factor in your consideration of the procedure now also.

Smack dab in the middle of the baby boomer generation, L.L. Woodard is a proud resident of "The Red Man" state. With what he hopes is an everyman's view of life's concerns both in his state and throughout the nation, Woodard presents facts and opinions based on common-sense solutions.

Thursday, June 9, 2011

S.Africa nearly wipes out infant AIDS infections: study (AFP)

CAPE TOWN (AFP) – South Africa's programme to prevent HIV in babies has achieved a 96.5 percent success rate in wiping out transmission from infected pregnant mothers, the Medical Research Council said Thursday.

An inaugural national evaluation survey among the world's biggest AIDS population tested 9,915 infants at public clinics, of whom 31.4 percent were exposed to the virus but only 3.5 percent tested positive, the government research body said.

"This survey was the first-ever rigorous national... evaluation in the nine provinces of South Africa," said Ameena Goga of the MRC.

Infection rates among mothers ranged from 15.6 percent in the sparsely populated Northern Cape to 43.9 percent in KwaZulu-Natal, which is the hardest hit region in the country.

Babies aged between four and eight weeks between June and December last year were tested at 580 sites across South Africa.

The study will be repeated this year and in 2012 to evaluate transmission rates over three years and the babies will be tracked up until they are 18 months old.

Last year, South Africa introduced new anti-AIDS drugs guidelines that include treatment for mothers at an earlier stage of illness.

The government was previously heavily criticised for refusing to roll out the life-saving drugs, but 1.4 million people are now on treatment.

The virus infects 5.6 million of the 50-million population, according to UN estimates.

Study finds why smokers gain weight when they quit (AP)

WASHINGTON – Scientists say they've finally discovered why smokers tend to gain some weight when they kick the habit.

It turns out that nicotine can rev up brain cells that normally signal people to stop eating when they're full, researchers report in Friday's edition of the journal Science.

The weight connection isn't huge: On average, quitters gain less than 10 pounds. Still, it's a worry that many smokers cite when asked why they don't try to quit. Now the question is whether the discovery might lead to better treatments to help them quit without worrying about weight.

Yale University associate research scientist Yann Mineur stumbled onto the connection while studying a nicotine-related substance in mice — and the animals suddenly started eating less.

Nicotine hooks onto a variety of receptors, or docking sites, on the surface of cells. That's how it triggers addiction in one part of the brain.

But when it comes to weight, the Yale research found that both nicotine and the related drug cytisine were activating a different receptor than the one involved in addiction. This one is located on a small set of neurons in the hypothalamus, a region that regulates appetite.

When they gave nicotine to mice without that cellular pathway, it didn't help them lose weight like it did normal mice.

Smoking causes cancer, heart attacks and a host of other ailments so worry about modest weight gain shouldn't deter someone from quitting. But smokers who do have that concern should try nicotine-based smoking-cessation treatments, said study senior author Marina Picciotto, a Yale professor of psychiatry and neurobiology.

The other drug used in the mouse experiments, cytisine, is sold in Eastern Europe for smoking cessation but not in the U.S., and she'd like to see if there's data on the weight of smokers abroad who've used it.

Developing a drug to target only these specific receptors would be difficult, she cautions, because they're also involved in the body's stress responses in ways that could lead to such side effects as high blood pressure.

Women Exposed to Combat Trauma as Resilient as Men: Study (HealthDay)

TUESDAY, June 7 (HealthDay News) -- Male and female military personnel exposed to combat zone trauma tend to experience similar mental health problems and recover at the same rate, a new study reveals.

The finding -- the first to examine the role of gender on combat-linked stress after deployment -- was based on a survey completed by American men and women deployed between October 2007 and July 2008 in Iraq and Afghanistan.

The study had two major findings, according to lead author Dawne S. Vogt, an associate professor of psychiatry at Boston University School of Medicine. "One is that more women than ever before are experiencing combat. So although men continue to experience it at slightly higher rates, the difference in exposure is relatively small."

"The other one is that this suggests that women may be just as resilient as men in the year following return from deployment," Vogt said. "Which is a novel finding, because the broader trauma literature has historically found that women are more vulnerable to trauma exposure. But in this study you're not seeing that."

Vogt and her colleagues present their findings in a recent online issue of the Journal of Abnormal Psychology.

The authors noted that the Pentagon's current official policy bars women from direct participation in ground combat, although they are nonetheless deployed in numerous risky combat situations.

That official ban has been the subject of much recent debate, despite the fact that according to the Department of Defense, more than 750 women have been killed or wounded in action in either the Iraq and Afghanistan wars as of 2009.

Against that backdrop, the study authors polled a random sample of 595 veterans of those wars through the Defense Manpower Data Center. The group was comprised of 340 women and 252 men, all of whom had returned from their respective war zone within the year leading up to the survey.

The male soldiers were more likely to be married and have children, while the women were three years younger on average, and more likely to be from a minority group. Half of the survey participants were "active duty," a quarter were part of the National Guard, and another quarter were part of the Reserve Forces.

Each soldier was asked whether or not he or she had fired a weapon, been shot at, and/or been witness to combat death or injuries. Post-battle experiences were also tallied, in terms of the handling or observing of human remains and contact with prisoners.

In addition, the survey explored the degree to which each soldier feared for his or her safety and well-being, along with the pressures and difficulties of day-to-day living in a combat zone. Participants were also asked to discuss their pre-deployment exposure to trauma and their exposure to sexual harassment on duty.

All the responses were then compared to each soldier's post-deployment history of post-traumatic stress disorder (PTSD), depression, substance abuse, and overall mental health functioning.

Vogt and her team first noted that while the male soldiers were exposed to slightly more combat and post-battle trauma, the traumatic nature of the group's combat experience was fairly similar across gender lines. Women were found to have experienced a greater degree of pre-deployment stress, as well as a greater incidence of sexual harassment while deployed.

In terms of post-deployment experience, male and female soldiers appeared to experience about the same degree of PTSD and depression in the year post-deployment. Mental health functioning was also comparable among male and female veterans, although substance abuse was more common among the men.

The authors concluded that male and female soldiers appear to be equally resilient to the stress and trauma of combat, in least in the immediate months following battle.

"One implication is I think people need to realize that women are experiencing combat too, even though at slightly lower levels," noted Vogt, who is also a researcher at the National Center for PTSD at the VA Boston Healthcare System. "And therefore that needs to be taken into consideration when they come home, in the context of caring for them in the health care setting."

"And the other implication," she said, "is that these findings are particularly relevant given the recent call for the military to reverse its long-standing policy barring women from ground combat."

For his part, Keith A. Young, vice chair for research in the department of psychiatry at Texas A&M Health Science Center in College Station, Texas, said the current insights are what he would expect.

"I'm not so surprised that military women experience similar mental health problems as men," said Young, who is also the Neuroimaging and Genetics core leader for the VA Center of Excellence for Research on Returning War Veterans in Waco, Texas.

"There is certainly the idea that has been out there that women are more susceptible to PTSD," Young said. "But I think a lot of the research wasn't very well controlled, and, in fact, in most of the animal work that has been done, it's the male animal that has been most susceptible to stress and PTSD. The female animals have actually proven to be more resilient."

Young cautioned, however, that the principle factor driving the current female combat ban may have less to do with concerns over vulnerability to combat trauma and more to do with the risk of abuse that women prisoners of war might face. In that light, he suggested that the current findings would not necessarily alter the current ban debate.

"Nevertheless, I think this finding will generally help women who are interested in a military career," he added. "It will help justify their ability to pursue that type of career and life."

Vogt's study was partially funded by a Department of Veterans Affairs Health Sciences Research and Development Service grant and the National Center for Posttraumatic Stress Disorder.

More information

For more on combat and PTSD, visit the U.S. National Institute of Mental Health.

Key to Better Sex Revealed in New Study (LiveScience.com)


People who can better communicate and understand another person's emotions are more likely to have a satisfying sex life, new research finds.


Personal attributes such as self-esteem and autonomy also play a role in sexual pleasure and health, the researchers said.


"Sexual health includes sexual well-being, and sexual enjoyment is an important part [of that]," said study researcher Adena Galinsky, of Johns Hopkins Bloomberg School of Public Health. "How people interact and their ability to listen to each other and take each other's perspective can really influence the sex that they have." [Top 10 Aphrodisiacs]


The study analyzed data from about 3,200 students, ages 18 to 26, who were surveyed between 2001 and 2002 as part of the third wave of the National Longitudinal Study of Adolescent Health.


Studying sexual satisfaction


Respondents answered questions meant to gauge levels of autonomy, self-esteem and empathy, along with their sexual health and satisfaction. Autonomy is defined as the strength to follow personal convictions even when they go against conventional wisdom, which usually increases as adolescents age and enter adulthood, Galinsky said. Self-esteem is a belief in one's self-worth, which also increases with age. Empathy is the ability to take another's perspective, to see things from their angle and understand and respond to their emotions.


The study found that men were more likely than women to report having orgasms most or all of the time during sex, with 87 percent of men saying so, compared with 47 percent of women in the study. Men were also more likely to enjoy giving oral sex to their partner more than women were, the study found.


"The reality is that the majority of young men really like engaging in activities in which the goal is giving their partner pleasure," Galinsky told LiveScience. "There is a pretty consistent difference between young men and young women."


When the researchers compared the personality attributes with the three measures of sexual satisfaction (frequency of orgasm, enjoyment level for giving and receiving oral sex) they found that higher levels of self-esteem, autonomy and empathy were associated with greater total sexual pleasure in females, but only empathy had an impact in men.


In men, autonomy alone was positively correlated to the frequency of orgasm, while only higher self-esteem was linked to the enjoyment of giving oral sex.


Getting emotional in the bedroom


"Our hypothesis is that empathetic individuals are more responsive to a partner’s needs, and thus initiate a positive feedback cycle," said Galinsky. "These developmental assets may be more important to young women’s sexual pleasure since they help them break down impediments to sexual communication and exploration," he said, referring to the idea that women are more inhibited in the bedroom.


Interestingly, recent data reported by Sara Konrath at the annual meeting of the Association for Psychological Science has shown that this type of empathy is dropping in adolescents and emerging adults, which might affect their sexual satisfaction. Females traditionally score higher in empathy and lower on self-esteem compared with their male counterparts.


Galinsky and her team are continuing to study sexual well being and satisfaction at all points of life, including in middle-age and older adults.


The study was published June 3 in the Journal of Adolescent Health.


You can follow LiveScience staff writer Jennifer Welsh on Twitter @microbelover. Follow LiveScience for the latest in science news and discoveries on Twitter @livescience and on Facebook.

Thursday, June 2, 2011

Obesity Greater Risk for Fatty Liver Than Alcohol, Study Finds (HealthDay)

THURSDAY, June 2 (HealthDay News) -- Obesity and insulin resistance constitute a greater risk for fatty liver disease than moderate alcohol consumption, according to a new study that found drinking modest amounts of red wine posed no greater risk for developing the condition.

For their study, published online May 23 in Annals of Medicine, Swedish researchers instructed 44 people to either abstain from alcohol or drink one (women) or two (men) glasses of red wine a day for three months. At the beginning and end of the three months, the investigators collected blood samples and conducted MRIs to measure the fatty content of participants' livers.

"It turned out that the amount of fat in the liver was linked with obesity and insulin resistance and was almost not at all affected by the red wine. Specifically, after three months, none of the wine drinkers had developed fatty liver or elevated liver transaminases," Dr. Stergios Kechagias, a liver specialist at Linkoping University, said in a news release from the Swedish Research Council.

Moreover, the study found a 16 percent decrease in levels of harmful LDL cholesterol among those who drank the red wine. "There is a strong correlation between moderate intake of alcohol and decreased risk of cardiovascular disease, and our data provides a mechanism for this since LDL cholesterol was lowered to such a large extent," Dr. Fredrik Nystrom, a professor at Linkoping, concluded in the news release.

Because it's known that large amounts of alcohol contribute to liver disease, it was long thought that even moderate consumption might have a harmful effect.

Fatty liver, which is associated with diabetes, high blood pressure and cardiovascular disease, can lead to cirrhosis of the liver, the researchers noted.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more information on fatty liver disease.

Thursday, May 19, 2011

Study: Homosexuality, celibacy didn't cause abuse (AP)

WASHINGTON – Researchers commissioned by the nation's Roman Catholic bishops to analyze the pattern of clergy sex abuse so dioceses could better identify offenders have concluded that homosexuality, celibacy and an all-male priesthood did not cause the scandal.

The study by the John Jay College of Criminal Justice in New York instead said that the problem was largely the result of poor seminary training and insufficient emotional support for men ordained in the 1940s and 1950s, who were not able to withstand the social upheaval they confronted as pastors in the 1960s. Crime and other deviant behavior increased overall in the United States during this period, when the rate of abuse by priests was climbing.

"The rise in abuse cases in the 1960s and 1970s was influenced by social factors in society generally," the report's authors said. "Factors that were invariant during the time period addressed, such as celibacy, were not responsible for the increase or decline in abuse cases over this time."

Victims' groups dismissed the report as an attempt to focus blame for the scandal on priests, instead of on bishops who allowed offenders to stay in ministry without warning parents or police. "They want us to fixate on abusive priests, not callous bishops," the Survivors Network of those Abused by Priests said in a statement.

The report, set to be released Wednesday, is the third study commissioned by the U.S. Conference of Catholic Bishops in 2002, when the abuse crisis erupted in the Archdiocese of Boston and caused what church leaders have called the deepest crisis in American Catholicism. A person close to the bishops provided an early copy to The Associated Press on condition of anonymity since the person was not authorized to release the information.

The scandal has cost U.S. dioceses nearly $3 billion and has spread to Europe and beyond. Just this week, Vatican officials instructed bishops worldwide to develop discipline policies for abusive priests within a year.

The debate over why priest-abusers were kept in ministry in the U.S. often fell along ideological lines. Liberals blamed mandatory celibacy or the lack of women in the church hierarchy, while conservatives blamed gay priests, since the overwhelming majority of known victims were boys.

The John Jay researchers, however, said that the offenders chose to victimize boys mainly because clergy had greater access to them. The study notes that gay men began enrolling in seminaries in larger numbers in the late 1970s and early 1980s, at a time when the rate of abuse was declining.

The authors, in findings first reported by Religion News Service, said they found "no single cause" of child sex abuse by priests and no "psychological characteristics" or "developmental histories" that distinguished guilty priests from clergy who did not molest children.

Although the victims studied by the researchers were all minors, the authors said only a tiny percentage of accused priests — less than 5 percent — could be technically defined as pedophiles. The John Jay researchers define pedophile as an adult with an intense sexual attraction to prepubescent children. However, victim advocates have disputed that classification by age, since boys ages 10 to 14 were the largest group of known victims, which could include children who had not yet gone through adolescence. The American Psychiatric Association defines pedophilia as attraction to children, usually age 13 or younger.

According to previous studies conducted by John Jay and other surveys commissioned by the bishops, U.S. dioceses have received abuse claims from more than 15,700 people against about 6,000 clerics since 1950. Abuse cases peaked in the 1970s, then began declining sharply in 1985, as the bishops and society general gained awareness about molestation and its impact on children, the study said.

Dioceses reported that nearly all of the allegations they received were reported after 2002 in response to intense news coverage of the problem and after child victims gained courage as adults to come forward. John Jay researchers said this means that the bishops were not aware of the true scope of the problem until then, an assertion victims' groups say is naive.

Critics argue the study cannot be trusted since the raw data was provided by the bishops.

In February, a Philadelphia grand jury alleged that the local archdiocese kept 37 credibly accused clergy in public ministry, despite repeated pledges by the nation's bishops that no offenders would stay on duty. In response, Philadelphia Cardinal Justin Rigali suspended about two dozen clergy and hired a former prosecutor to review the cases. Ana Maria Catanzaro, the head of the Philadelphia review board, which was formed to advise bishops on abuse cases, said last week that the archdiocese had "failed miserably at being open and transparent" and had kept some cases from the board.

"What Philadelphia does is reveal the flaws in the process," said Ann Barrett Doyle of the advocacy group BishopAccountability.org, which is compiling a public database of all records related to the scandal.

Sister Mary Ann Walsh, a spokeswoman for the bishops' conference, said church leaders fully cooperated with the $1.8 million study, which was funded by the bishops, Catholic foundations, individual donors and a grant from the U.S. Department of Justice. Dioceses have spent tens of millions of dollars since 2002 on child safety programs that include background checks for people who work with children and training for adults and children to identify abuse.

"John Jay was chosen to do the study because of its independence from the church," Walsh said. "John Jay was free to consult whomever they wanted and they did so."